Infrastructure and services
Equipment
The groups involved in the program have several instrumental and analytical techniques, which represent a large proportion of infrastructure required to carry out the programs and to be available for the rest of the participant groups. Here are as follows:UAH-QACSIC-AACSIC-AIUCM-QAUNED-QACQAB-147URJC-284
UAH-QA Group
- Capillary liquid chromatograph (micro-LC)
- 3 liquid chromatograph (HPLC) with ultraviolet (UV) and fluorescence detector, one of them with a fraction collector
- 4 capillary electrophoresis (CE)
- 2 mass spectrometer, one of them with quadrupole-time of flight detector (QTOF) and the other one with an ion trap (IT), both coupled to a HPLC, microLC and CE
- Protein fractionator by off-gel isoelectric focusing
- Gel electrophoresis
- Spectrophotometer UV-Vis
Furthermore, this group has access to different Research Support Centre in Alcalá University.
CSIC-AA Group
- Capillary electrophoresis (CEDAD)
- 2 Liquid chromatograph coupled to refraction index (IR), UV-Vis with diode array detector (DAD) and fluorescence
- Liquid chromatograph coupled to refraction index detection and DAD for molecular exclusion
- Liquid chromatograph coupled to tipple quadrupole mass spectrometer
- Gas chromatograph with flame ionization detector (GCFID)
- UVVISfluorescence plate reader
- Preparative lab equipment
Moreover, this group has access to the Research Support Centre of ICTAN-CSIC where two pilot plants for food processing are highlighted, a sensorial analysis unity with experimental cooking and tasting rooms, refrigeration plant, and cell cultures unit, among others. Of special relevance is the Access to the instrumental, microbiological and analytical techniques unit (belong to RED-LAB) which has a wide range of scientific instrumentation (ionic chromatography, 3 GC-MS and two of them with head space, atomic absorption, HPLCQQQ, HPLCQToF, libraries, etc.).
CSIC-AI Group
- 2 gas chromatograph with flame ionization detector
- 3 gas chromatograph coupled to a quadrupole mass spectrometer
- Two dimensional gas chromatograph GC x GC, with an electron capture detector
- Gas chromatograph coupled to triple quadrupole mass spectrometer
- Gas chromatograph with an electron capture detector
- Gas chromatograph coupled to a chemical ionization mass spectrometer
- Multidimensional gas chromatograph (heart-cut) with electron capture detectors
- Pressurized liquid extraction
- Microwave assisted extraction
- UV-Vis absorption at fixed wavelengths
- Two dimensional gas chromatograph GC x GC, with mass spectrometer ToF detector
- HPLC coupled to quadrupole mass spectrometer
- UPLC coupled to triple quadrupole mass detector
UCM-QA Group
- 3 ICPMS for trace analysis coupled to HPLC
- AF 4 and laser ablation for the study of species transformation and characterization, quantitation and nanoparticles location
- LCQTOFMS
- LCMS
- Several GC coupled to MS and ECD detectors
- Several HPLC coupled to Fluorescence and DAD detector
- Liquid chromatograph with traveling valves for LC-LC coupling for conventional and capillary columns
- Mercury analyser
- Simple treatment systems such as microwave digester, ultrasounds probe and PLE
- QPCR and separation systems for gel Electrophoresis
Moreover, this group has access to the Research Support Centre of UCM including electronic microscopy of CAI, mass spectrometry of CAI and x-ray diffraction of CAI.
UNED-QA Group
- 3 liquid chromatographs with DAD, fluorescence, ion and MS detectors
- Gas chromatograph with FID and MS detectors
- 2 UV-VIS spectrophotometers
- Spectrofluorometer
- Attenuated total internal reflection (ATR) with infrared spectroscopy
- Extraction oven with microwaves
- Scanning electron microscopy SEM (COXEM) EM-30AX PLUS.
CQAB-147 Laboratory
- Emission spectroscopy by ICP plasma
- UV-Vis spectrophotometer
- Fluorescence spectrophotometer
- Gas chromatograph (Star CX 3800/AS 8200 and headspace)
- Gas chromatograph of Agilent Tech
- GC/MS of Agilent Tech
- HPLC (Star 9020 (PolyChrom) turned into a GPC with ELS)
- Preparative HPLC Dynamax with 2 pumps SD1 and 1 pump SD300
- 2 HPLCMS of Agilent Tech
- Capillary Electrophoresis system of Agilent CE
- 4 HPLC 1200 of Agilent Tech
- HPLC 1200 with fluorescence detector of Agilent Tech
- HPLC coupled to a Triple Quad LC/MS Agilent 6410
- UHPLC coupled to an Orbitrap accurate mass detector of Thermo
- Ion chromatograph 850 Metrohm
- IR spectrometer
- Rheometer Haake Mars of Thermo
- Differential Scanning Calorimetric of MettlerToledo DSC822.
- Viscometer Schott Visco Easy Plus
- Muffle Carbolite CWF 1100
- centrifuge Eppendorf 5804R
- Distiller and titrator Kjeldahl
- Microwave oven Milestone
- SpeedVac ThermoSavans
- Titrator 702SM Metrohm
- Titrator KarlFischer 701KF Metrohm
- KF Coulometrico 831 Metrohm con Thermoprep 860
- pH meter 692 Metrohm
- Conductometer 712 Metrohm
- Analytical balance up to five places after the decimal point
- Micropipettes
- 3 climatic camera Binder de 250 a 700 L
- Freeze-dryer
- Fash Biotage SP1 system
- Reactors and bioreactors up to 400L, with wide range of temperature and pressure for the synthesis of organic and inorganic compounds and biotechnological processes
URJC-284 Laboratory
- Fisisorption of gas system ASAP 2020
- HPLC with triple quad mass detector Varian1200LC
- UHPLC Dionex with ion trap AmaZon of Bruker
- HPLC-DAD VarianProStar
- Capillary Electrophoresis Beckman Coulter P/ACE MDQ DAD and UV/vis detectors
- Potentiostat/Galvanostat of Metrohm Autolab ECOCHEMIE model PGSTAT302
- 2 MiniBipotentiostat μSTAT200 Dropsens
- Spectrometer Cary 60 UVVIS of Agilent
- Spectrometer FTIR of Thermo Nicolet 380FTIR
- High vacuum lines, extraction boxes, centrifuges, etc., for simple treatment
Through the Technology Support Center of URJC the access to these techniques is reduced cost:
- X-ray diffraction and fluorescence
- nuclear magnetic resonance spectroscopy for liquids and solids
- Thermo gravimetric analysis
- scanning electron microscope
- Transmission electron microscope
Mechanic workshop (allowing the development and design of components for the investigation in different materials: metal, polymers and Teflon)
Service offers
CQAB-147URJC-284
CQAB-147 Laboratory
The technical services this lab is offering embraced 4 areas:
- Bio analysis and quality control
- Biotechnology
- Organic synthesis
- New materials, energy and the recovery of waste
Which include the following services:
- Isolation and elucidation of unknown compounds, natural extracts, intermedies of drugs and medicines.
- Development and validation of new analytical methods
- Analysis of raw materials and final product
- Bio analysis of organic compounds in physiological fluids through liquid chromatography coupled to orbitrap or triple quad
- Liquid, gas and ion chromatography
- Accurate mass determination
- Metal determination
- Calorimetric studies
- Reologic studies
- Stability studies
- Product purification
- Chemical synthesis of any organic or inorganic compound
- Determination of the solvent purity
- Study of residual solvents in drugs and medicines
- Polymer synthesis and characterization
- Synthesis of products in degradation
- Synthesis and escalated in new drugs
- Improve procedures for the generic drug synthesis
- Tuning and escalating of biotechnological processes with recombinant microorganism
- Obtaining raw materials and/or solid fuel recovered from urban wastes
- Use of biomass
- Hydrogenation reactions
- Pressure reactions
- Escalating chemical processes to pre-industrial levels
- Extraction of aromatic natural essences
- Obtaining proteins and enzymes
URJC-284 Laboratory
The technical services this lab is offering embraced 3 areas:
- Electrochemical techniques
- Separation and simple preparation techniques
- Characterization techniques
Which include the following services:
- Electrochemical study of organic and inorganic samples in aqueous and non-aqueous medium
- Analysis of heavy metals through electrochemical techniques
- Separation and quantitation of chiral and non-quiral compounds through HPLCDAD, HPLCMS/MS and UPLCMS/MS in environmental samples, drugs, food and chemical industry products, etc.
- Separation and quantitation of chiral and non-quiral compounds through CEDAD in environmental samples, drugs, food and chemical industry products, etc.
- Sample treatment: water, food and drugs
- Method development, report and advice for their implementation
- Determination of textural properties in mesoporous materials